Chilled water cooling systems consume nearly 50% of building energy required to meet cooling loads, especially in hot, humid climates.1 Chiller COP can be improved with the optimal chilled water supply temperature, and significant amounts of system energy can be reduced. Similarly, chilled water distribution pumps designed with high temperature delta T will have less annual energy consumption compared to low delta T chilled water system design. The optimal chilled water supply temperature needs to be determined based on space dehumidification factor, since a high chilled water supply temperature leads to a decrease in the cooling coil latent load capacity and a potential increase in the size of cooling coils. This study examined the impact of chilled water (CHW) supply temperature on the chiller’s efficiency, the effects of CHW temperature differentials on pump energy consumption and the most suitable CHW supply temperature for space dehumidification.